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It will have been given to you to help keep your mood within normal limits by helping to control the episodes of mania. Abbott Chem. Patients receiving daily doses higher than 45 mg/kg/day body weight should be carefully monitored. The generally accepted therapeutic range for total valproic acid steady-state concentrations is 50–100 μg/mL, although some clinicians suggest drug concentrations as high as 175 μg/mL.

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020) and for time to hospitalization also no statistically significant difference in the HR for the two drugs (HR = 0. . You can take it with or without food. For enteric coated sodium valproate at a dose of 500 mg (valproic acid equivalent 433 mg) twice a day it is 91.